Medical Fiber Optics

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I. INTRODUCTION, METHODOLOGY & PRODUCT DEFINITION

Study Reliability And Reporting Limitations

Disclaimers

Data Interpretation & Reporting Level

Quantitative Techniques & Analytics

Product Definitions And Scope Of Study

Introduction

Fiberoptic Surgical Lights

Fiberoptic Dental Lights

Endoscopes

Laser Fiberoptics

Fiberoptic Sensors

Other Fiberoptic Products

II. EXECUTIVE SUMMARY

1. Global Market Overview

Medical Fiber Optics - An Overview

Current & Future Analysis

Medical OEMs Benefit from Specialty Applications

Areas of Growth for Suppliers

Photodynamic Therapy

More Efficient Fibers for Minimally Invasive Surgery

2. Focus on Fiber Optic Technology

Advantages of Optical Fibers over Conventional Copper Wires

Optical Fiber Bundles/Imaging Multi-fibers

Multi-fiber Bundles - Small Fibers Put Together

Distal Lens Systems Help in Viewing Large Images

Types of Optical Fibers/Multi-fibers

Plastic Multi-fibers

Silica and Glass Multi-fibers

Rigid Multi-fibers

3. Review of Key Components in Fiber Optic Instruments

Key Components

A. Fiber Optic Cables

B. Fiber Optic Light Sources

Conventional Light Sources

Low-Intensity and High-Intensity Light Sources

Transmission of Light into the Fiber

Arc Lamps

LEDs

LEDs and Wound Healing

4. Medical Fiber Optic Product Segments

Introduction

Fiberoptic Surgical Lights

Fiberoptic Dental Lights

Endoscopes

Use of Fiber Optics in Endoscopes

Rigid and Flexible Endoscopes

Endoscope Channels

Types of Fibers Used

Light Sources Used

Applications of Endoscopes

Detection of Stomach and Esophageal Ailments

Photodynamic Therapy

Endoscopic Examinations

Amnioscopic Surgery

Fiber Optic Rhinoscopy

Percutaneous Fiberscopes

Other Fiberscopes Using Fiber Optic Illumination and Imaging

Gastrofiberscopes or Gastroscopes

Bronchoscopes

Cytoscopes

Colonoscopes

Enteroscopes

Laparoscopes

Arthroscopes

Laryngoscopes

Fiber Optic Lasers

Optical Fibers - The Appropriate Beam Delivery Systems

Types of Lasers and Associated Need for Optical Fiber Beam Delivery Systems

Fiber Optic Catheters

Catheter Technologies

50 Micron Catheter from Advance Interventional Systems

Developments in Fiber Optic Catheters

Select Laser Surgeries Using Optical Fibers

Laser Ablation of the Prostrate

To Shrink Enlarged Prostrate Glands

Photodynamic Therapy

Destruction of Tumors

Fiber Optic Sensors

Design of Sensors

Applications of Various Types of Sensors

Temperature Sensors

Pressure Sensors

Glucose Sensors

Blood Gas Sensors

Other Sensors

Intra-Arterial Blood Gas Monitoring Systems (IABGS)

Silica Fibers - The Most Widely Used Fibers

Disadvantages of Using Plastic and Glass Fibers in Sensors

Associated Instruments

Competitive Scenario

Regulations & Reimbursement Issues

Other Fiberoptic Products

5. Risks Associated with High-Intensity Light

Tissue Damage Due to Radiation

Bonding Problems Due to Heat

Methods to Check High-intensity Light Problems

Dichroic Filters to Check Infrared Radiation Problems

Reflectors and Dichroic Mirrors Used to Negate Heat

Irradiance Meters - Warning Systems

Control and Maximization of Light

Methods to Maximize Light Intensity

6. Application of Fiber Optics in Medical Information Transfer

Fiber Optic Channels

Fiber Channel - A New Fiber-Optic Medical Imaging Network

Superhighway for Medical Telecommunications

Telemedicine - An Innovative Application of Fiber Optic Networks

7. Technology Developments

Light Emitting Diodes for Treatment of Cancer Patients

Online Lung Cancer Exam System

Infrared Transmitting Fiber-Optic Endoscope

Vein Center of Virginia Develops Innovative Low- Intensity Laser Therapy

Historic Developments

Fiber Optic Pressure Sensor to Measure Blood Pressure

Cylindrical Light Diffuser Based on Polymer Optical Fiber

Multi-Analyte Fiber Optic Sensor Modelled on the Olfactory System

A Superfine Fiberscope to View Tympactic Cavity

A New Fiber Optic Probe For Imaging

OCT - A Diagnostic Tool for Capturing Microscopic Images

8. Product Introductions/Innovations

StockerYale Releases Specialty Optical Fibers

Cardiogenesis Receives FDA Approval for PMC Clinical Trial

Omni-Tract Surgical Unveils Single-Use Omni Bright™ Surgical Light

Spectranetics Unveils CLiRpath 2. 5 Turbo Catheter

Development of Projection Lamp Adjustment Apparatus

OptiLED Rolls Out The S6 LED Pseudo-Filament Lamp

Biophan Grabs Two New Patents

Trimedyne Embarks on ‘Hydrostat’ Development

Coherent Unveils 940 nm and 980 nm FAP Diode Lasers

Laserscope Launches Advanced GreenLight™ Laser System

Laserscope Launches Solis™

PerkinElmer Launches XL3000 Fiber Optic Illuminator

Smith & Nephew Launches SOLIS™ Surgical Illuminator

Laserscope Introduces Gemini Laser System

VISILED Launches Wireless Surgical Headlight

Poly-Optical Introduces Fiber Optic Panels

Luxtec Introduces 9300XSP

Luxtec Corp Launches Light-emitting Diodes with in- Build Lenses

Steris Corp. Develops Deepsite™ Fiber Optic Surgical Light

Getinge Introduces FiberLux™ Surgical Illumination System

Enlightened Technologies Introduces Prototype of Eyeglasses Using Fiber Optic Cables

AngioLaz Inc XenaLux Fiber-Optic Surgical Headlamp

9. Recent Industry Activity

American Medical Systems Acquires Laserscope

Laserscope Acquires InnovaQuartz

Excel Terminates Merger Agreement with Coherent

Bruker BioSciences Acquires Bruker Optics

Spectranetics Enters into Research Collaboration with BioScan

Cardiogenesis Shifts to New Facility

Coherent Acquires Assets of Iolon

ADC Acquires Fiber Optic Network Solutions

Bel Announces Acquisition of Netwatch

PENTAX Europe Acquires Sistemas

OptiLED Shifts Products to Traxon

Laserscope Signs Distribution Agreement with MD International

Light BioScience Clears FDA Approval for GentleWaves

ARA Installs Lightpointe’s Optical Wireless Systems

Laserscope Receives Patent for GreenLight PV

Fibertech Networks Receives Contract from Baystate Health System

3M and Advanced Interconnect to Provide Single- Mode OGI Multi-Fiber Systems

Flextronics Buys Wave Optics and Fico Fiber Optics

Cooper Acquires Lumax™ Fiber Optic Cystometry System

Trimedyne Acquires Mobile Surgical Technologies, Inc.

Samsung Corning Micro-Optics to Increase Production Capability

Agilent Technologies to Expand Fiberoptics Production Capacity

Lucent Microelectronics Group Forms Joint Venture with DiCon Fiberoptics

10. Focus on Select Global Players

Applied Fiberoptics (US)

Biolitec AG (Germany)

CardioGenesis Corporation (US)

Coherent (US)

Getinge AB (Sweden)

MAQUET SA (France)

Laserscope (US)

Steris Corp. (US)

The Spectranetics Corporation (US)

Trimedyne, Inc. (US)

11. Global Market Perspective

Table 1: World Recent Past, Current & Future Analysis for Medical Fiber Optics by Geographic Region - US, Canada, Japan, Europe, Asia-Pacific (excluding Japan), and Latin America Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2000 through 2010 (includes corresponding graph/chart)

Table 2: World 10-Year Perspective For Medical Fiber Optics by Geographic Region - Percentage Breakdown of Dollar Sales for US, Canada, Japan, Europe, Asia-Pacific (Excluding Japan), and Latin America Markets For Years 2000, 2006 & 2010 (includes corresponding graph/chart)

Table 3: World Recent Past, Current & Future Analysis for Fiberoptic Surgical Lights by Geographic Region - US, Canada, Japan, Europe, Asia-Pacific (excluding Japan), and Latin America Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2000 through 2010 (includes corresponding graph/chart)

Table 4: World 10-Year Perspective for Fiberoptic Surgical Lights by Geographic Region - Percentage Breakdown of Dollar Sales for US, Canada, Japan, Europe, Asia-Pacific (excluding Japan), and Latin America Markets for Years 2000, 2006 & 2010 (includes corresponding graph/chart)

Table 5: World Recent Past, Current & Future Analysis for Fiberoptic Dental Lights by Geographic Region - US, Canada, Japan, Europe, Asia-Pacific (Excluding Japan), and Latin America Markets Independently Analyzed With Annual Sales Figures In US$ Million For Years 2000 Through 2010 (includes corresponding graph/chart)

Table 6: World 10-Year Perspective for Fiberoptic Dental Lights by Geographic Region - Percentage Breakdown of Dollar Sales for US, Canada, Japan, Europe, Asia-Pacific (excluding Japan), and Latin America Markets for Years 2000, 2006 & 2010 (includes corresponding graph/chart)

Table 7: World Recent Past, Current & Future Analysis for Endoscopes by Geographic Region - US, Canada, Japan, Europe, Asia-Pacific (Excluding Japan), and Latin America Markets Independently Analyzed With Annual Sales Figures In US$ Million For Years 2000 Through 2010 (includes corresponding graph/chart)

Table 8: World 10-Year Perspective for Endoscopes by Geographic Region - Percentage Breakdown of Dollar Sales for US, Canada, Japan, Europe, Asia-Pacific (excluding Japan), and Latin America Markets for Years 2000, 2006 & 2010 (includes corresponding graph/chart)

Table 9: World Recent Past, Current & Future Analysis for Laser Fiberoptics by Geographic Region - US, Canada, Japan, Europe, Asia-Pacific (Excluding Japan), and Latin America Markets Independently Analyzed With Annual Sales Figures In US$ Million For Years 2000 Through 2010 (includes corresponding graph/chart)

Table 10: World 10-Year Perspective for Laser Fiberoptics by Geographic Region - Percentage Breakdown of Dollar Sales for US, Canada, Japan, Europe, Asia-Pacific (excluding Japan), and Latin America Markets for Years 2000, 2006 & 2010 (includes corresponding graph/chart)

Table 11: World Recent Past, Current & Future Analysis for Fiberoptic Sensors by Geographic Region - US, Canada, Japan, Europe, Asia-Pacific (Excluding Japan), and Latin America Markets Independently Analyzed With Annual Sales Figures In US$ Million For Years 2000 Through 2010 (includes corresponding graph/chart)

Table 12: World 10-Year Perspective for Fiberoptic Sensors by Geographic Region - Percentage Breakdown of Dollar Sales for US, Canada, Japan, Europe, Asia-Pacific (excluding Japan), and Latin America Markets for Years 2000, 2006 & 2010 (includes corresponding graph/chart)

Table 13: World Recent Past, Current & Future Analysis for Other Medical Fiberoptic Products by Geographic Region - US, Canada, Japan, Europe, Asia-Pacific (Excluding Japan), and Latin America Markets Independently Analyzed With Annual Sales Figures In US$ Million For Years 2000 Through 2010 (includes corresponding graph/chart)

Table 14: World 10-Year Perspective for Other Medical Fiberoptic Products by Geographic Region - Percentage Breakdown of Dollar Sales for US, Canada, Japan, Europe, Asia-Pacific (excluding Japan), and Latin America Markets for Years 2000, 2006 & 2010 (includes corresponding graph/chart)

III. MARKET

1. The United States

A. Market Analysis

US - The Largest Market

Product Introductions/Innovations

Recent Industry Activity

Key Players

Applied Fiberoptics

CardioGenesis Corporation

Coherent

Laserscope

Luxtec Corporation

Steris Corp.

The Spectranetics Corporation

Trimedyne, Inc.

B. Market Analytics

Table 15: US Recent Past, Current & Future Analysis for Medical Fiber Optics by Product Segment - Fiberoptic Surgical Lights, Fiberoptic Dental Lights, Endoscopes, Laser Fiberoptics, Fiberoptic Sensors and Other Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2000 through 2010 (includes corresponding graph/chart)

Table 16: US 10-Year Perspective for Medical Fiber Optics by Product Segment - Percentage Breakdown of Dollar sales for Fiberoptic Surgical Lights, Fiberoptic Dental Lights, Endoscopes, Laser Fiberoptics, Fiberoptic Sensors and Other Markets for 2000, 2006 & 2010 (includes corresponding graph/chart)

2. Canada

Market Analysis

Table 17: Canadian Recent Past, Current & Future Analysis for Medical Fiber Optics by Product Segment - Fiberoptic Surgical Lights, Fiberoptic Dental Lights, Endoscopes, Laser Fiberoptics, Fiberoptic Sensors and Other Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2000 through 2010 (includes corresponding graph/chart)

Table 18: Canadian 10-Year Perspective for Medical Fiber Optics by Product Segment - Percentage Breakdown of Dollar sales for Fiberoptic Surgical Lights, Fiberoptic Dental Lights, Endoscopes, Laser Fiberoptics, Fiberoptic Sensors and Other Markets for 2000, 2006 & 2010 (includes corresponding graph/chart)

3. Japan

Market Analysis

Table 19: Japanese Recent Past, Current & Future Analysis for Medical Fiber Optics by Product Segment - Fiberoptic Surgical Lights, Fiberoptic Dental Lights, Endoscopes, Laser Fiberoptics, Fiberoptic Sensors and Other Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2000 through 2010 (includes corresponding graph/chart)

Table 20: Japanese 10-Year Perspective for Medical Fiber Optics by Product Segment - Percentage Breakdown of Dollar sales for Fiberoptic Surgical Lights, Fiberoptic Dental Lights, Endoscopes, Laser Fiberoptics, Fiberoptic Sensors and Other Markets for 2000, 2006 & 2010 (includes corresponding graph/chart)

4. Europe

A. Market Analysis

Key Players

Getinge AB (Sweden)

MAQUET SA (France)

B. Market Analytics

Table 21: European Recent Past, Current & Future Analysis for Medical Fiber Optics by Geographic Region - France, Germany, Italy, UK, & Rest of Europe Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2000 through 2010 (includes corresponding graph/chart)

Table 22: European Recent Past, Current & Future Analysis for Medical Fiber Optics by Product Segment - Fiberoptic Surgical Lights, Fiberoptic Dental Lights, Endoscopes, Laser Fiberoptics, Fiberoptic Sensors and Other Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2000 through 2010 (includes corresponding graph/chart)

Table 23: European 10-Year Perspective for Medical Fiber Optics by Geographic Region - Percentage Breakdown of Dollar sales for France, Germany, Italy, UK, & Rest of Europe Markets for Years 2000, 2006 & 2010 (includes corresponding graph/chart)

Table 24: European 10-Year Perspective for Medical Fiber Optics by Product Segment - Percentage Breakdown of Dollar sales for Fiberoptic Surgical Lights, Fiberoptic Dental Lights, Endoscopes, Laser Fiberoptics, Fiberoptic Sensors and Other Markets for 2000, 2006 & 2010 (includes corresponding graph/chart)

4a. France

Market Analysis

Table 25: French Recent Past, Current & Future Analysis for Medical Fiber Optics by Product Segment - Fiberoptic Surgical Lights, Fiberoptic Dental Lights, Endoscopes, Laser Fiberoptics, Fiberoptic Sensors and Other Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2000 through 2010 (includes corresponding graph/chart)

Table 26: French 10-Year Perspective for Medical Fiber Optics by Product Segment - Percentage Breakdown of Dollar sales for Fiberoptic Surgical Lights, Fiberoptic Dental Lights, Endoscopes, Laser Fiberoptics, Fiberoptic Sensors and Other Markets for 2000, 2006 & 2010 (includes corresponding graph/chart)

4b. Germany

A. Market Analysis

Biolitec AG - A Key Player

B. Market Analytics

Table 27: German Recent Past, Current & Future Analysis for Medical Fiber Optics by Product Segment - Fiberoptic Surgical Lights, Fiberoptic Dental Lights, Endoscopes, Laser Fiberoptics, Fiberoptic Sensors and Other Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2000 through 2010 (includes corresponding graph/chart)

Table 28: German 10-Year Perspective for Medical Fiber Optics by Product Segment - Percentage Breakdown of Dollar sales for Fiberoptic Surgical Lights, Fiberoptic Dental Lights, Endoscopes, Laser Fiberoptics, Fiberoptic Sensors and Other Markets for 2000, 2006 & 2010 (includes corresponding graph/chart)

4c. Italy

Market Analysis

Table 29: Italian Recent Past, Current & Future Analysis for Medical Fiber Optics by Product Segment - Fiberoptic Surgical Lights, Fiberoptic Dental Lights, Endoscopes, Laser Fiberoptics, Fiberoptic Sensors and Other Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2000 through 2010 (includes corresponding graph/chart)

Table 30: Italian 10-Year Perspective for Medical Fiber Optics by Product Segment - Percentage Breakdown of Dollar sales for Fiberoptic Surgical Lights, Fiberoptic Dental Lights, Endoscopes, Laser Fiberoptics, Fiberoptic Sensors and Other Markets for 2000, 2006 & 2010 (includes corresponding graph/chart)

4d. The United Kingdom

Market Analysis

Table 31: UK Recent Past, Current & Future Analysis for Medical Fiber Optics by Product Segment - Fiberoptic Surgical Lights, Fiberoptic Dental Lights, Endoscopes, Laser Fiberoptics, Fiberoptic Sensors and Other Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2000 through 2010 (includes corresponding graph/chart)

Table 32: UK 10-Year Perspective for Medical Fiber Optics by Product Segment - Percentage Breakdown of Dollar sales for Fiberoptic Surgical Lights, Fiberoptic Dental Lights, Endoscopes, Laser Fiberoptics, Fiberoptic Sensors and Other Markets for 2000, 2006 & 2010 (includes corresponding graph/chart)

4e. Rest of Europe

Market Analysis

Table 33: Rest of Europe Recent Past, Current & Future Analysis for Medical Fiber Optics by Product Segment - Fiberoptic Surgical Lights, Fiberoptic Dental Lights, Endoscopes, Laser Fiberoptics, Fiberoptic Sensors and Other Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2000 through 2010 (includes corresponding graph/chart)

Table 34: Rest of Europe 10-Year Perspective for Medical Fiber Optics by Product Segment - Percentage Breakdown of Dollar sales for Fiberoptic Surgical Lights, Fiberoptic Dental Lights, Endoscopes, Laser Fiberoptics, Fiberoptic Sensors and Other Markets for 2000, 2006 & 2010 (includes corresponding graph/chart)

5. Asia Pacific

Market Analysis

Table 35: Asia Pacific Recent Past, Current & Future Analysis for Medical Fiber Optics by Product Segment - Fiberoptic Surgical Lights, Fiberoptic Dental Lights, Endoscopes, Laser Fiberoptics, Fiberoptic Sensors and Other Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2000 through 2010 (includes corresponding graph/chart)

Table 36: Asia Pacific 10-Year Perspective for Medical Fiber Optics by Product Segment - Percentage Breakdown of Dollar sales for Fiberoptic Surgical Lights, Fiberoptic Dental Lights, Endoscopes, Laser Fiberoptics, Fiberoptic Sensors and Other Markets for 2000, 2006 & 2010 (includes corresponding graph/chart)

6. Latin America

A. Market Analysis

Strategic Corporate Development

B. Market Analytics

Table 37: Latin American Recent Past, Current & Future Analysis for Medical Fiber Optics by Product Segment - Fiberoptic Surgical Lights, Fiberoptic Dental Lights, Endoscopes, Laser Fiberoptics, Fiberoptic Sensors and Other Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2000 through 2010 (includes corresponding graph/chart)

Table 38: Latin American 10-Year Perspective for Medical Fiber Optics by Product Segment - Percentage Breakdown of Dollar sales for Fiberoptic Surgical Lights, Fiberoptic Dental Lights, Endoscopes, Laser Fiberoptics, Fiberoptic Sensors and Other Markets for 2000, 2006 & 2010 (includes corresponding graph/chart)

IV. COMPETITION

1. 3M Company (USA)

Table 39: Annual Sales Analysis: 2004-2006 (In US$ billion)

Table 40: Annual Sales Analysis by Quarter: 2006 Vs. 2005 (In US$ billion)

Table 41: Annual Sales Analysis by Segment: 2006 Vs. 2005 (In US$ billion)

Table 42: Annual Sales Analysis by Geographic Region: 2006 Vs. 2005 (In US$ billion)

Table 43: Annual Sales Analysis by Quarter: 2005 Vs. 2004 (In US$ billion)

Table 44: Annual Sales Analysis by Segment: 2005 Vs. 2004 (In US$ billion)

Table 45: Annual Sales Analysis by Geographic Region: 2005 Vs. 2004 (In US$ billion)

2. Advanced Interconnect, Inc. (USA)

3. Advantage Medical Cables, Inc. (USA)

4. Agilent Technologies, Inc. (USA)

Table 46: Annual Sales Analysis: 2004-2006 (In US$ million)

Table 47: Annual Sales Analysis by Quarter: 2005 Vs. 2004 (In US$ million)

Table 48: Annual Sales Analysis by Business Segment: 2005 Vs. 2004 (In US$ million)

Table 49: Annual Sales Analysis by Geographic Region: 2005 Vs. 2004 (In US$ million)

5. Alcatel-Lucent (France)

6. American Medical Systems, Inc. (USA)

Table 50: Annual Sales Analysis: 2004-2006 (In US$ million)

Table 51: Annual Sales Analysis by Quarter: 2005 Vs. 2004 (In US$ million)

Table 52: Annual Sales Analysis by Product: 2005 Vs. 2004 (In US$ million)

Table 53: Annual Sales Analysis by Geographic Region: 2005 Vs. 2004 (In US$ million)

Laserscope, Inc. (USA)

Table 54: First Quarter Sales Analysis: 2006 Vs. 2005 (In US$ million)

Table 55: Annual Sales Analysis: 2005 Vs. 2004 (In US$ million)

Table 56: Annual Sales Analysis by Quarter: 2005 Vs. 2004 (In US$ million)

Table 57: Annual Sales Analysis by Business Segment: 2005 Vs. 2004 (In US$ million)

Table 58: Annual Sales Analysis by Geographic Region: 2005 Vs. 2004 (In US$ million)

7. Applied Fiberoptics, Inc. (USA)

8. Arthrex, Inc. (USA)

9. BFW, Inc. (USA)

10. Biolitec AG (Germany)

Table 59: First Quarter Sales Analysis: 2007 Vs. 2006 (In € million)

Table 60: Annual Sales Analysis: 2004-2006 (In € million)

Table 61: Annual Sales Analysis by Product: 2006 Vs. 2005 (In € million)

Table 62: Annual Sales Analysis by Geographic Region: 2006 Vs. 2005 (In € million)

CeramOptec GmbH (Germany)

11. Biophan Technologies, Inc. (USA)

12. Boston Scientific Corporation (USA)

Table 63: Half Yearly Sales Analysis: 2006 Vs. 2005 (H1) (In US$ million)

Table 64: Half Yearly Sales Analysis by Segment: 2006 Vs. 2005 (H1) (In US$ million)

Table 65: Half Yearly Sales Analysis by Geographic Region: 2006 Vs. 2005 (H1) (In US$ million)

Table 66: Annual Sales Analysis: 2005 Vs. 2004 (In US$ million)

Table 67: Annual Sales Analysis by Quarter: 2005 Vs. 2004 (In US$ million)

Table 68: Annual Sales Analysis by Segment: 2005 Vs. 2004 (In US$ million)

Table 69: Annual Sales Analysis by Geographic Region: 2005 Vs. 2004 (In US$ million)

13. Bruker BioSciences Corporation (USA)

Table 70: Nine Months Sales Analysis: 2006 Vs. 2005 (Nine Months Ended, September) (In US$ million)

Table 71: Nine Months Sales Analysis by Segment: 2006 Vs. 2005 (Nine Months Ended, September) (In US$ million)

Table 72: Annual Sales Analysis: 2005 Vs. 2004 (In US$ million)

Table 73: Annual Sales Analysis by Quarter: 2005 Vs. 2004 (In US$ million)

Table 74: Annual Sales Analysis by Segment: 2005 Vs. 2004 (In US$ million)

Table 75: Annual Sales Analysis by Geographic Region: 2005 Vs. 2004 (In US$ million)

14. Bryan Corporation (USA)

15. Canada Endoscope Corporation (Canada)

16. Cardinal Health, Inc. (USA)

Table 76: First Quarter Sales Analysis: 2007 Vs. 2006 (In US$ million)

Table 77: First Quarter Sales Analysis by Segment: 2007 Vs. 2006 (In US$ million)

Table 78: Annual Sales Analysis: 2006 Vs. 2005 (In US$ million)

Table 79: Annual Sales Analysis by Segment: 2006 Vs. 2005 (In US$ million)

Table 80: Annual Sales Analysis by Geographic Region: 2006 Vs. 2005 (In US$ million)

17. CardioGenesis Corporation (USA)

Table 81: Nine Months Sales Analysis: 2006 Vs. 2005 (Nine Months Ended, September) (In US$ million)

Table 82: Nine Months Sales Analysis by Quarter: 2006 Vs. 2005 (Nine Months Ended, September) (In US$ million)

Table 83: Annual Sales Analysis: 2005 Vs. 2004 (In US$ million)

Table 84: Annual Sales Analysis by Quarter: 2005 Vs. 2004 (In US$ million)

18. Carsen Medical, Inc. (Canada)

19. Chiu Technical Corporation (USA)

20. Clarus Medical LLC (USA)

21. Coherent, Inc. (USA)

Table 85: Nine Months Sales Analysis: 2006 Vs. 2005 (Nine Months Ended, June) (In US$ million)

Table 86: Nine Months Sales Analysis by Quarter: 2006 Vs. 2005 (Nine Months Ended, June) (In US$ million)

Table 87: Nine Months Sales Analysis by Geographic Region: 2006 Vs. 2005 (Nine Months Ended, June) (In US$ million)

Table 88: Annual Sales Analysis: 2005 Vs. 2004 (In US$ million)

Table 89: Annual Sales Analysis by Quarter: 2005 Vs. 2004 (In US$ million)

Table 90: Annual Sales Analysis by Business Segment: 2005 Vs. 2004 (In US$ million)

Table 91: Annual Sales Analysis by Geographic Region: 2005 Vs. 2004 (In US$ million)

22. Corning, Inc. (USA)

Table 92: Nine Months Sales Analysis: 2006 Vs. 2005 (Nine Months Ended, September) (In US$ million)

Table 93: Nine Months Sales Analysis by Quarter: 2006 Vs. 2005 (Nine Months Ended, September) (In US$ million)

Table 94: Nine Months Sales Analysis by Segment: 2006 Vs. 2005 (Nine Months Ended, September) (In US$ million)

Table 95: Annual Sales Analysis: 2005 Vs. 2004 (In US$ million)

Table 96: Annual Sales Analysis by Quarter: 2005 Vs. 2004 (In US$ million)

Table 97: Annual Sales Analysis by Segment: 2005 Vs. 2004 (In US$ million)

Table 98: Annual Sales Analysis by Geographic Region: 2005 Vs. 2004 (In US$ million)

Samsung Corning Micro-Optics (South Korea)

23. Designs For Vision, Inc. (USA)

24. DiCon Fiberoptics, Inc. (USA)

25. Dolan-Jenner Industries, Inc. (USA)

26. Electro Standards Laboratories, Inc. (USA)

27. Electro-Surgical Instruments Company (USA)

28. Elmed, Inc. (USA)

29. Endoscopy Support Services, Inc. (USA)

30. Enlightened Technologies Associates, Inc. (USA)

31. Escalon Medical Corporation (USA)

Table 99: Half Yearly Sales Analysis: 2007 Vs. 2006 (H1) (In US$ million)

Table 100: Annual Sales Analysis: 2006 Vs. 2005 (In US$ million)

32. Excel Technology, Inc. (USA)

Table 101: Annual Sales Analysis: 2004-2006 (In US$ million)

Table 102: Annual Sales Analysis by Quarter: 2006 Vs. 2005 (In US$ million)

Table 103: Annual Sales Analysis by Geographic Region: 2006 Vs. 2005 (In US$ million)

Table 104: Annual Sales Analysis by Quarter: 2005 Vs. 2004 (In US$ million)

Table 105: Annual Sales Analysis by Geographic Region: 2005 Vs. 2004 (In US$ million)

33. Fiberguide Industries (USA)

34. Fiberoptic Systems, Inc. (USA)

35. Fiberoptics Technology, Inc. (USA)

36. Fibertech Networks LLC (USA)

37. Flextronics International Ltd. (Singapore)

Table 106: Half Yearly Sales Analysis: 2007 Vs. 2006 (H1) (In US$ million)

Table 107: Half Yearly Sales Analysis by Geographic Region: 2007 Vs. 2006 (H1) (In US$ million)

Table 108: Annual Sales Analysis: 2006 Vs. 2005 (In US$ million)

Table 109: Annual Sales Analysis by Geographic Region: 2006 Vs. 2005 (In US$ million)

38. Fujinon Corporation (Japan)

39. Getinge AB (Sweden)

Table 110: Annual Sales Analysis: 2004-2006 (In SEK million)

Table 111: Annual Sales Analysis by Quarter: 2005 Vs. 2004 (In SEK million)

Table 112: Annual Sales Analysis by Segment: 2005 Vs. 2004 (In SEK million)

Maquet SA (France)

40. Gyrus Acmi (USA)

41. Hellma Cells, Inc. (USA)

42. Infrared Fiber Systems, Inc. (USA)

43. Integra Lifesciences Holdings Corporation (USA)

Table 113: Nine Months Sales Analysis: 2006 Vs. 2005 (Nine Months Ended, September) (In US$ million)

Table 114: Nine Months Sales Analysis by Segment: 2006 Vs. 2005 (Nine Months Ended, September) (In US$ million)

Table 115: Nine Months Sales Analysis by Geographic Region: 2006 Vs. 2005 (Nine Months Ended, September) (In US$ million)

Table 116: Annual Sales Analysis: 2005 Vs. 2004 (In US$ million)

Table 117: Annual Sales Analysis by Quarter: 2005 Vs. 2004 (In US$ million)

Table 118: Annual Sales Analysis by Product: 2005 Vs. 2004 (In US$ million)

Integra Neurosciences (USA)

44. Invotec International, Inc. (USA)

45. Isolux LLC (USA)

46. Jedmed Instrument Company (USA)

47. Karl Storz GmbH (Germany)

Karl Storz Endoscopy-America, Inc. (USA)

Karl Storz Endoscopy Canada Ltd. (Canada)

48. Kashmir Surgical Works (India)

49. Kelleher Medical, Inc. (USA)

50. Light Bioscience LLC (USA)

51. Luxtec Corporation (USA)

52. Machida Borescopes (USA)

53. Med-Electronics, Inc. (USA)

54. Medtronic, Inc. (USA)

Table 119: Half Yearly Sales Analysis: 2007 Vs. 2006 (H1) (In US$ million)

Table 120: Half Yearly Sales Analysis by Quarter: 2007 Vs. 2006 (H1) (In US$ million)

Table 121: Half Yearly Sales Analysis by Business Segment: 2007 Vs. 2006 (H1) (In US$ million)

Table 122: Half Yearly Sales Analysis by Geographic Region: 2007 Vs. 2006 (H1) (In US$ million)

Table 123: Annual Sales Analysis: 2004-2006 (In US$ million)

Table 124: Annual Sales Analysis by Business Segment: 2006 Vs. 2005 (In US$ million)

Table 125: Annual Sales Analysis by Geographic Region: 2006 Vs. 2005 (In US$ million)

Table 126: Annual Sales Analysis by Business Segment: 2005 Vs. 2004 (In US$ million)

Table 127: Annual Sales Analysis by Geographic Region: 2005 Vs. 2004 (In US$ million)

55. Meshtel-Intelite, Inc. (USA)

56. Nanoptics, Inc. (USA)

57. Newport Corporation (USA)

Table 128: Annual Sales Analysis: 2004-2006 (In US$ million)

Table 129: Annual Sales Analysis by Quarter: 2006 Vs. 2005 (In US$ million)

58. Nikon, Inc. (USA)

59. OFS (USA)

60. Olympus Corporation (Japan)

Table 130: Annual Sales Analysis: 2004-2006 (In ¥ million)

Table 131: Annual Sales Analysis by Segment: 2006 Vs. 2005 (In ¥ million)

Table 132: Annual Sales Analysis by Geographic Region: 2006 Vs. 2005 (In ¥ million)

Table 133: Annual Sales Analysis by Segment: 2005 Vs. 2004 (In ¥ million)

Table 134: Annual Sales Analysis by Geographic Region: 2005 Vs. 2004 (In ¥ million)

Olympus America, Inc. (USA)

61. Optiled Technologies LLC (USA)

62. Optim, Inc. (USA)

63. O' Ryan Industries (USA)

64. Osram Sylvania (USA)

65. Pentax Corporation (Japan)

Table 135: Annual Sales Analysis: 2006 Vs. 2005 (In ¥ million)

Table 136: Annual Sales Analysis by Segment: 2006 Vs. 2005 (In ¥ million)

Table 137: Annual Sales Analysis by Geographic Region: 2006 Vs. 2005 (In ¥ million)

Pentax of America, Inc. (USA)

66. PerkinElmer, Inc. (USA)

Table 138: Nine Months Sales Analysis: 2006 Vs. 2005 (Nine Months Ended, September) (In US$ million)

Table 139: Nine Months Sales Analysis by Quarter: 2006 Vs. 2005 (Nine Months Ended, September) (In US$ million)

Table 140: Nine Months Sales Analysis by Business Segment: 2006 Vs. 2005 (Nine Months Ended, September) (In US$ million)

Table 141: Annual Sales Analysis: 2005 Vs. 2004 (In US$ million)

Table 142: Annual Sales Analysis by Quarter: 2005 Vs. 2004 (In US$ million)

Table 143: Annual Sales Analysis by Business Segment: 2005 Vs. 2004 (In US$ million)

Table 144: Annual Sales Analysis by Geographic Region: 2005 Vs. 2004 (In US$ million)

67. Philips Medical Systems (USA)

Philips Lumileds Lighting Company (USA)

68. Poly-Optical Products, Inc. (USA)

69. Prima Medical Systems Ltd. (UK)

70. Progressive Dynamics, Inc. (USA)

71. Richard Wolf GmbH (Germany)

Richard Wolf Medical Instruments Corporation (USA)

Richard Wolf Austria Ges MbH (Austria)

Richard Wolf France Sarl (France)

Richard Wolf UK Ltd. (UK)

72. Schott AG (Germany)

Table 145: Annual Sales Analysis: 2005 Vs. 2004 (In € million)

Table 146: Annual Sales Analysis by Geographic Region: 2005 Vs. 2004 (In € million)

Schott North America, Inc. - Fiber Optics (USA)

73. Smith & Nephew PLC (UK)

Table 147: Nine Months Sales Analysis: 2006 Vs. 2005 (Nine Months Ended, September) (In US$ million)

Table 148: Nine Months Sales Analysis by Segment: 2006 Vs. 2005 (Nine Months Ended, September) (In US$ million)

Table 149: Nine Months Sales Analysis by Geographic Region: 2006 Vs. 2005 (Nine Months Ended, September) (In US$ million)

Smith & Nephew Endoscopy Division (USA)

74. Solos Endoscopy, Inc. (USA)

75. Specialty Surgical Instrumentation (USA)

76. Spectranetics Corporation, The (USA)

Table 150: Annual Sales Analysis: 2004-2006 (In US$ million)

Table 151: Annual Sales Analysis by Product: 2005 Vs. 2004 (In US$ million)

Table 152: Annual Sales Analysis by Geographic Region: 2005 Vs. 2004 (In US$ million)

77. Steris Corporation (USA)

Table 153: Annual Sales Analysis: 2006 Vs. 2005 (In US$ million)

Table 154: Annual Sales Analysis by Segment: 2006 Vs. 2005 (In US$ million)

Table 155: Annual Sales Analysis by Geographic Region: 2006 Vs. 2005 (In US$ million)

78. StockerYale, Inc. (USA)

Table 156: Nine Months Sales Analysis: 2006 Vs. 2005 (Nine Months Ended, September) (In US$ million)

Table 157: Nine Months Sales Analysis by Quarter: 2006 Vs. 2005 (Nine Months Ended, September) (In US$ million)

Table 158: Nine Months Sales Analysis by Business Segment: 2006 Vs. 2005 (Nine Months Ended, September) (In US$ million)

Table 159: Nine Months Sales Analysis by Geographic Region: 2006 Vs. 2005 (Nine Months Ended, September) (In US$ million)

Table 160: Annual Sales Analysis: 2005 Vs. 2004 (In US$ million)

Table 161: Annual Sales Analysis by Business Segment: 2005 Vs. 2004 (In US$ million)

Table 162: Annual Sales Analysis by Geographic Region: 2005 Vs. 2004 (In US$ million)

79. Stryker Corporation (USA)

Table 163: Nine Months Sales Analysis: 2006 Vs. 2005 (Nine Months Ended, September) (In US$ billion)

Table 164: Nine Months Sales Analysis by Segment: 2006 Vs. 2005 (Nine Months Ended, September) (In US$ billion)

Table 165: Nine Months Sales Analysis by Geographic Region: 2006 Vs. 2005 (Nine Months Ended, September) (In US$ billion)

Table 166: Annual Sales Analysis: 2005 Vs. 2004 (In US$ billion)

Table 167: Annual Sales Analysis by Segment: 2005 Vs. 2004 (In US$ billion)

Table 168: Annual Sales Analysis by Geographic Region: 2005 Vs. 2004 (In US$ billion)

80. Teleflex Medical Group (USA)

81. Timbercon, Inc. (USA)

82. Toshiba Medical Systems Corporation (Japan)

83. Trimedyne, Inc. (USA)

Table 169: First Quarter Sales Analysis: 2007 Vs. 2006 (In US$ million)

Table 170: First Quarter Sales Analysis by Segment: 2007 Vs. 2006 (In US$ million)

Table 171: First Quarter Sales Analysis by Product and Service: 2007 Vs. 2006 (In US$ million)

Table 172: Annual Sales Analysis: 2006 Vs. 2005 (In US$ million)

Table 173: Annual Sales Analysis by Segment: 2006 Vs. 2005 (In US$ million)

Table 174: Annual Sales Analysis by Product and Service: 2006 Vs. 2005 (In US$ million)

84. TTI Medical (USA)

85. Tyco Healthcare Group LP (USA)

86. Ushio America, Inc. (USA)

87. Vicon Fiber Optics Corporation (USA)

88. VisiLED Corporation (USA)

89. Wavien, Inc. (USA)

90. Welch Allyn, Inc. (USA)